Vague thoughts at the moment:  to read the entire history of philosophy, premised on Presence, as an immunological response to media.  Everything in Parmenides and Plato suggests this.  It is all there in Plato’s Allegory of the Cave: the opposition between rhetoric and philosophy, the denigration of labor, the strange suspicion of writing, the privilege of the subject over the collective, and the eclipse of the thing by the concept.  Clearly Derrida everywhere here.  Why this horror of mediation?  Why this horror of the material?